Faculty Information - GOTOH Takaya |


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GOTOH Takaya Faculty of Sports and Health Science Department of Health Science（Graduate School of Sports and Health Science Sports and Health Science） Professor

■ Academic background

1.		Kagawa Medical University Faculty of Medicine Graduated
2.	1992/04～1995/03	Kagawa Medical University Graduate School, Division of Medicine〔Doctoral course〕 Completed

■ Business career

2004/04～2011/03

Jichi Medical University Faculty of Medicine

■ Books and Papers

1.	Paper	PKC-delta deficiency inhibits fetal development and is associated with heart elastic fiber hyperplasia and lung inflammation in adult PKC knockout mice (Collaboration) 2021/07
2.	Paper	Glyosylation is a novel TGFb-independent post-tranaslational modification of Smasd2 (Collaboration) 2020/01
3.	Paper	Novel function of HATs and HDACs in homologous recombination through acetylation of human RAD52 at double-strand break sites. (Collaboration) 2018/03
4.	Paper	Characteristics of three-dimensional prospectively isolated mouse bone marrow mesenchymal stem/stromal cell aggregates on nanoculture plates (Collaboration) 2016/04
5.	Paper	Assessing the applicability of FISH-based prematurely condensed dicentric chromosome assay in triage biodosimetry (Collaboration) 2014/10
6.	Paper	Radiation increases the cellular uptake of exosomes through CD29/CD81 complex formation. (Collaboration) 2014/01
7.	Paper	Vitronection improves cell survival after radiation injury in human umbilical vein endothelial cells. (Collaboration) 2013/12
8.	Paper	A modified protocol for accurate detection of cell fusion-mediated premature chromosome condensation in human peripheral blood lymphocytes (Collaboration) 2013/07
9.	Paper	Clinical Impact of Radiation-Resistant Mesenchymal Stem Cells in Bone Marrow Deduced from Preclinical Studies (Collaboration) 2013/04
10.	Paper	Outline of the TEPCO Fukushima Dai-ichi Nuclear Power Plant accident (Collaboration) 2012
11.	Paper	Depot-specific expression of lipolytic genes in human adipose tissues--association among CES1 expression, triglyceride lipase activity and adiposity (Collaboration) 2011/09
12.	Paper	A single nucleotide polymorphism in the FADS1/FADS2 gene is associated with plasma lipid profiles in two genetically similar Asian ethnic groups with distinctive differences in lifestyle (Collaboration) 2010/06
13.	Paper	Regulatory SNP in the RBP4 gene modified the expression in adipocytes and associated with BMI (Collaboration) 2010/05
14.	Paper	Large scale replication analysis of loci associated with lipid concentrations in a Japanese population (Collaboration) 2009/06
15.	Paper	Genetic heterogeneity in a susceptible region for essential hypertension among demographically different local populations in Japan. (Collaboration) 2008/11
16.	Paper	Comparative study of polymorphisms on genes associated with lifestyle related diseases in Asian and Pacific populations (Collaboration) 2008/10
17.	Paper	Identification of a regulatory SNP in the retinol binding protein 4 gene associated with type 2 diabetes in Mongolia (Collaboration) 2007/02
18.	Paper	An intronic variable number of tandem repeat polymorphisms of the cold-induced autoinflammatory syndrome 1 (CIAS1) gene modifies gene expression and is associated with essential hypertension (Collaboration) 2006/12
19.	Paper	Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB (Collaboration) 2004/04
20.	Paper	The high-risk human papillomavirus type 16 E6 counters the GAP function of E6TP1 toward small Rap G proteins (Collaboration) 2003/01
21.	Paper	Prenylation of target GTPases contributes to signaling specificity of Ras-guanine nucleotide exchange factors (Collaboration) 2001/04
22.	Paper	Regulation of Ras signaling specificity by protein kinase C (Collaboration) 2001/04
23.	Paper	Expression and subcellular localization of multifunctional calmodulin-dependent protein kinases-I, -II and -IV are altered in rat hippocampal CA1 neurons after induction of long-term potentiation (Collaboration) 2000/08
24.	Paper	Activation of R-Ras by Ras-guanine nucleotide-releasing factor (Collaboration) 1997/07
25.	Paper	Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nuceleotide-releasing factor C3G (Collaboration) 1995/12
26.	Paper	Hodikin's disease and Sjogren Syndrome (Collaboration) 1993/03
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■ Academic conference presentation

1.	2012/06	Fukushima Nuclear Accident (European Association of Poisons Centres and clinical Toxicologist, XXXII International Congress,)
2.	2001/08	Prenylation of target GTPases contributes to signaling specificity of RasGRF (Gordon Conference,)
3.	2000/09	Differential Regulation of Ras Effector Signaling by Protein Kinase C (16th Annual Meeting On Oncogenes)
4.	1996/03	Identification of Rap1 as a target for the Crk SH3 Domain-Binding Guanine Nucleoide Releasing Factor C3G (Kystone Symposia On Molecular & Cellular Biology)