Faculty Information - HIRAO Maki |


日本語 >>	TOP page

HIRAO Maki Faculty of Sports and Health Science Department of Health Science Professor

■ Present specialized field

Sports Medicine, General physiology

■ Academic background

1.	1990/10～1993/06	Dimond High School, Anchorage, Alaska, U.S.A. Graduated
2.	1993/09～1994/05	Boston University, Massachusetts, U.S.A., College of Liberal Arts,
3.	1994/05～1997/05	Tufts University, Medford, Massachusetts, U.S.A., College of Liberal Arts, Graduated Bachelor of Science With High Honors in Thesis
4.	1997/05～1998/05	University of California, Davis, U.S.A., Program in Physiology,〔Doctoral course〕
5.	1998/06～2003/12	University of Washington, Seattle, Washington, U.S.A., Program in Biomolecular Structure and Design,〔Doctoral course〕 Completed Doctor of Philosophy in Chemistry
6.	2005/04～2009/03	Hokkaido University School of Medicine Graduated Doctor of Medicine
5 display
All display(6)

■ Business career

1.	1996/09～1996/11	Tufts University, Cells and Organisms Laboratory, Teaching Assistant
2.	1998/06～2003/12	University of Washington/Fred Hutchinson Cancer Research Center, Clinical Research Division and Public Health Sciences Division, Research Assistant
3.	2000/03～2000/06	University of Washington, Cell Biology, Molecular Biology of Disease, Teaching Assistant
4.	2009/04～2011/03	Tokyo Saiseikai Central Hospital
5.	2011/04～2015/03	Tokyo Saiseikai Central Hospital Division of Hematology, Department of Medicine
6.	2015/04～2023/03	Tokyo Saiseikai Central Hospital Division of Hematology, Department of Medicine
5 display
All display(6)

■ Belonging society

2013/02～

International Myeloma Society

■ Activity in society

1.	1991/09～1991/09	Chinook Elementary School, Anchorage, Alaska, U.S.A., Visiting Lecture, Japanese Culture
2.	1996/06～1997/05	Massachusetts General Hospital, U.S.A., Emergency Room, Floor Assistant Volunteer

■ Winning science prize

1.	1991/05	National Honor Society for Secondary Schools, Member
2.	1991/05	The Alaska Legislature 1991 Excellence in Education Award, Honor Roll Student of Dimond High School
3.	1991/05	Who's Who Among American High School Students, 1990-1991 edition
4.	1992/04	Second place in 19th annual Anchorage School District High School Mathematics Competition
5.	1992/05	Merit Award: Outstanding Science Student of the Year (Dimond High School)
6.	1992/05	The Alaska Legislature 1992 Excellence in Education Award, Honor Roll Student of Dimond High School
7.	1992/05	Who's Who Among American High School Students, 1991-1992 edition
8.	1993/05	Anchorage School District High School Solo and Ensemble Festival, Outstanding Performer in Flute Solo
9.	1993/05	Atlantic-Pacific Mathematics League
10.	1993/05	Mu Alpha Theta National High School and Junior College Mathematics Club, Charter Member
11.	1993/05	State of Alaska Commendation Award in Recognition of Academic Achievements and Dedication to Learning
12.	1993/05	The Alaska Legislature 1993 Excellence in Education Award, Honor Roll Student of Dimond High School
13.	1993/06	Honor Graduate, Academic Excellence (Dimond High School)
14.	1993/06	Superintendent's Award for Meritorious Academic Achievement as a Four-year Honor Student (Dimond High School)
15.	1993/06	Tandy Technology Scholars, Academic Top Two Percent (Dimond High School)
16.	1994/12	College of Liberal Arts Dean's List Fall 1994 (Tufts University)
17.	1995/06	College of Liberal Arts Dean's List Spring 1995 (Tufts University)
18.	1995/09	Golden Key National Honor Society, Membership (Tufts University)
19.	1996/05	Howard Hughes Medical Institute: Undergraduate Research Fellows (Tufts University)
20.	1996/12	College of Liberal Arts Dean's List Fall 1994 (Tufts University)
21.	1997/05	High Honors in Thesis (Tufts University)
5 display
All display(21)

■ Books and Papers

1.	Paper	Immunomodulatory Effect of Proteasome Inhibitors via the Induction of Immunogenic Cell Death in Myeloma Cells (Collaboration) 2023/09
2.	Paper	Factors Associated with Refraining from Health Checkups during the COVID-19 Pandemic in Japan (Collaboration) 2023/08
3.	Paper	Novel Aldosterone Antagonists in Hypertension and Diabetic Kidney Disease (Collaboration) 2023/07
4.	Paper	GTN057, a komaroviquinone derivative, induced myeloma cells' death in vivo and inhibited c-MET tyrosine kinase (Collaboration) 2023/02
5.	Paper	Health state utilities of patients with hepatitis B and C and hepatitis-related conditions in Japan. (Collaboration) 2022/10
6.	Paper	Working conditions contribute to fertility-related quality of life: a cross-sectional study in Japan (Collaboration) 2022/07
7.	Paper	Rare evolution of CSF3R-mutated chronic neutrophilic leukemia to t(4;12)(q12;p13) acute myeloid leukemia with SETBP1 mutation (Collaboration) 2022/04
8.	Paper	Negative E-cadherin expression on bone marrow myeloma cell membranes is associated with extramedullary disease (Collaboration) 2022/02
9.	Paper	Integrin beta 5 and beta 7 expression in lenalidomide-resistant multiple myeloma cells (Collaboration) 2022/02
10.	Paper	Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia Incidentally Detected by Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography at a Health Checkup (Collaboration) 2022/02
11.	Paper	Total Hip Arthroplasty with a Cementless Acetabular Component and Impaction Bone Grafting for Dysplastic Osteoarthritis Complicated by Multiple Myeloma (Collaboration) 2022/02
12.	Paper	A novel homozygous variant of the thrombomodulin gene causes a hereditary bleeding disorder (Collaboration) 2021/10
13.	Paper	Detection of Bartonella quintana Infection among the Homeless Population in Tokyo, Japan, from 2013-2015 (Collaboration) 2021/09
14.	Paper	A novel derivative (GTN024) from a natural product, komaroviquinone, induced the apoptosis of high-risk myeloma cells via reactive oxygen production and ER stress (Collaboration) 2018/11
15.	Paper	Identification and characterization of Sir2 inhibitors through phenotypic assays in yeast (Collaboration) 2004/11
16.	Paper	Inhibitors of Sir2: evaluation of splitomicin analogues (Collaboration) 2004/05
17.	Paper	Identification of selective inhibitors of NAD⁺-dependent deacetylases using phenotypic screens in yeast (Collaboration) 2003/10
18.	Paper	NAD+-dependent deacetylase Hst1p controls biosynthesis and cellular NAD⁺ levels in Saccharomyces cerevisiae (Collaboration) 2003/10
19.	Paper	A chemical genetic approach for the identification of selective inhibitors of NAD(+)-dependent deacetylases (Single) 2003/09
20.	Paper	Localization of allin lyase mRNA in the garlic clove by in situ hybridization with digoxigenin-riboprobes (Single) 1997/06
5 display
All display(20)

■ Academic conference presentation

1.	2020/07	A Hereditary bleeding disorder caused by a novel homozygous mutation of thrombomodulin gene (The Congress of the International Society on Thrombosis and Hemostasis)
2.	2018/12	Immunomodulatory Effects of Proteasome Inhibitors in Multiple Myeloma (the 60th American Society of Hematology Annual Meeting and Exposition Annual Meeting)
3.	2018/07	Identification of clonal evolution of CSF3R-mutated chronic neutrophilic leukemia using mutational screens of SETBP1, ASXL1 and SRSF2 (the 9th JSH International Symposium)
4.	2003/03	Inhibitors of Sir2p: evaluation of Splitomicin analogues (the 225th American Chemical Society National Meeting)
5.	2003/02	Chemical genetics of NAD+-dependent protein deacetylases (the 12th Volcano Conference in Bioorganic Chemistry)

■ Research topic, funded research, and department laboratory expense

1996/06～1996/08

Howard Hughes Medical Institute Undergraduate Research Fellows (Tufts University), Localization of Allin Lyase mRNA in the Garlic Clove by in situ Hybridization with Digoxigenin-Riboprobes

■ Department laboratory expense researcher number

10902158

■ ReaD Researcher code

R000034596

■ E-Mail Address

■ Home Page

https://www.instagram.com/hirazemi/